Posted by: Jensen Hearing | April 11, 2006

Pains killers and hearing loss

Painkiller linked to hearing loss
.
Coincidentally, the House Ear Institute in Los Angeles, where Limbaugh sought treatment, discovered in 1999 that some of its patients with sudden hearing loss had overused a common painkiller that combines hydrocodone and acetaminophen. (29 patients)
The combination is sold under several brand names: Vicodin, Hydrocet, Norco and Lorcet. Lorcet is one of the prescriptions Limbaugh’s former housekeeper said she procured for him…
Poisoning and Poisons – News – Times Topics – The New York Times

News about poisoning and poisons. Commentary and archival information about poisoning and poisions from The New York Times. … listing of all the headlines in today’s New York Times … generic name of ingredient in Vicodin is hydrocodone bitartrate

Tylenol (paracetamol, also known as acetaminophen) is a popular American brand of pain reliever and fever reducer, sold by Johnson & Johnson. It is extremely popular because it is available without prescription and it is effective with few side effects, but overdoses of Tylenol are serious and can be fatal. In heavy drinkers, regular use of acetaminophen increases liver damage
Lee wants to copy Britain, which saw a 30 percent drop in severe liver poisonings after restricting how much acetaminophen could be bought at once.
HYDROCODONE
4,5a-Epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5)
IUPAC name

Legal status
Class A (UK), UK limited vicodin usse and cut back liver damage by 30%
Routes of administration
Oral

Hydrocodone or dihydrocodeinone (marketed as Vicodin, Anexsia, Dicodid, Hycodan, Hycomine, Lorcet, Lortab, Norco, Hydroco, Tussionex, Vicoprofen) is an opioid derived from either of the naturally occurring opiates codeine or thebaine. Hydrocodone is an orally active narcotic analgesic and antitussive. The typical therapeutic dose of 5 to 10 mg is pharmacologically equivalent to 30 to 60 mg of oral codeine.[citation needed] Sales and production of this drug have increased significantly in recent years, as have diversion and illicit

Hydrocodone Bitrate 10mg/
Acetaminophen 650mg
As a narcotic, hydrocodone relieves pain by binding to opioid receptors in the brain and spinal cord. It may be taken with or without food. When taken with alcohol, it can intensify drowsiness. It may interact with monoamine oxidase inhibitors, as well as other drugs that cause drowsiness. It is in FDA pregnancy category C: its effect on an embryo or fetus is not clearly known and pregnant women should consult their physicians before taking it. Common side effects include dizziness, lightheadedness, nausea, drowsiness, euphoria, vomiting, and constipation. Some less common side effects are allergic reaction, blood disorders, changes in mood, mental fogginess, anxiety, lethargy, difficulty urinating, spasm of the ureter, irregular or depressed respiration and rash.
Hydrocodone can be habit-forming , and can lead to physical and psychological addiction. In the U.S., pure hydrocodone and forms containing more than 15 mg per dosage unit are called hydrocodone compounds and are considered Schedule II drugs. Those containing less than 15 mg per dosage unit are Schedule III drugs. Hydrocodone is typically found in combination with other drugs such as paracetamol (acetaminophen), aspirin, ibuprofen and homatropine methylbromide. In the UK it is listed as a Class A drug under the Misuse of Drugs Act 1971.

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